Noninvasive detection and quantification of left-to-right shunts in children using oxygen-15 labeled carbon dioxide.
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چکیده
منابع مشابه
Noninvasive detection and quantification of left-to-right shunts in children using oxygen-15 labeled carbon dioxide.
A method for the detection and quantification of left-to-right intracardiac shunts is described which utilizes a single breath inhalation of oxygen-15 labeled carbon dioxide (C15O2). The inhaled gas rapidly crosses the alveolar membrane and the oxygen-15 label is exchanged through the carbonate cycle to form oxygen-15 labeled water within the pulmonary capillary blood. Pulmonary indicator clear...
متن کاملInhalation imaging with oxygen-15 labeled carbon dioxide for detection and quantitation of left-to-right shunts.
Quantitation of left-to-right shunts was determined noninvasively from the pulmonary clearance pattern of inhaled 15oxygen-labeled carbon dioxide (C15O2). After a single breath inhalation of C15O2, counts over the lungs were obtained from sequential 0.5 sec positron camera images. In 21 patients without left-to-right shunts, counts declined exponentially due to the washout of C15O2 by the pulmo...
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New technologies for the noninvasive assessment of oxygen and carbon dioxide are transforming clinical practice. Transcutaneous monitoring of PO2 (PtcO2) and PCO2 (PtCO2) provides an approximation of PaO2 and PaCO2 values in hemodynamically normal individuals, but both PtcO2 and PtcCO2 diverge from the corresponding arterial values when cardiac output is reduced, even in the absence of hypotens...
متن کاملLeft-to-Right Shunts
Contrary to the opinion of French pediatrician HenriLouis that isolated ventricular septal defects (VSDs) are universally well tolerated, the subsequent discoveries of Eisenmenger, Abbott, Wood, and others have taught us that the prognosis of left-to-right shunt lesions is not always benign. After more than a century of research, as pediatric cardiologists and congenital heart surgeons, we clai...
متن کاملBedside nuclear probe for detection and quantification of left to right intracardiac shunts.
A cadmium telluride nuclear probe with an Elscint gamma camera was used to detect and measure left to right intracardiac shunts at the bedside in 34 patients. Fifteen also had right heart catheterisation and oximetric measurement of the shunt. For the nuclear technique 740 MBq (20 mCi) of technetium-99m pertechnetate was injected into the right antecubital vein and the pulmonary to systemic flo...
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ژورنال
عنوان ژورنال: Circulation
سال: 1977
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.56.4.626